After the middle of Ming Dynasty，driven by the factors such as overseas trade and the development in mountainous areas，the market integration continue apace and led to some coastal business gathering places in the South China littoral and its hinterland． Meilu Town known as “Little Foshan”，located in western Guangdong，was representative of this trend． This paper discusses the formation，spatial pattern， and evolution of the social power structure of this town during the transition from the Ming to Qing Dynasty． From local unrest to the restructuring of social order; this article reveals the social networking of different groups in this particular time and space and the complex relationships between Meilu town and the larger area． This research helps us to have a deeper understanding of the market networks of Ming and Qing Dynasties and the social history of South China towns．